https://www.selleckchem.com/pr....oducts/fasoracetam-n
Cisplatin is a chemotherapeutic agent against solid cancers. However, neuropathy is a major side effect and has no effective treatment so far. Emerging evidence suggests that cisplatin might damage nerve capillaries leading to impaired blood-nerve barrier (BN. This study aimed to investigate the ultrastructural changes of the BNB in the sciatic nerves and dorsal root ganglia of rats with cisplatin neuropathy and the effects of B₁₋₆₋₁₂. The results showed that cisplatin 2 mg/kg injected intraperitoneally twice a week for 5 c