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88 ± 13.76 vs. 90.59 ± 10.75, 84.78 ± 14.86 vs. 87.28 ± 12.45, and 41.40 ± 9.77 vs. 45.40 ± 8.82, respectively, all P 0.05). DM was negatively correlated with the symptoms and problems (regression coefficient for log transformed [175-score] = 0.01 and the SF-12 physical function dimension (regression coefficient = - 2.18) (all P 0.05). HRQOL of diabetic patients with CKD was worse than that of non-diabetic patients with CKD. DM was an independent and negative factor affecting HRQOL in patients with CKD. HRQOL of diabetic patie
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