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Much of the plastic waste entering the sea is thought to be transported from land by rivers, yet little is known about the distances over which rivers transport plastic. To address this knowledge gap, we collected surface water samples from the Orange-Vaal River at the end of the wet and dry seasons. The Vaal River drains South Africa's main urban-industrial centre, whereas the upper Orange River is sparsely populated. Below their confluence, the river flows through increasingly arid regions with very low human populations before enteri