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While a statistically significant difference was found between the intervention group's and control group's mean scores in terms of the group, time, and group*time for the acute CINV (p0.05), there was no statistically significant difference for delayed CINV between groups scores in terms of the time, and group*time interaction (p0.05). This study supports the findings that the interactive mobile application was found effective in reducing CINV in children. Additionally, it can be said 5inD is more effective for the management of a