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Adequate removal of previous root filling materials is an important objective during endodontic retreatment. This study was aimed to evaluate the influence of obturation quality and sealer type on the removal of root filling materials during endodontic retreatment using micro-computed tomography (μ-CT). Ninety extracted mandibular premolars were randomly assigned to two groups ( = 45) based on the type of sealer (AH Plus and BioRoot RCS) and three sub-groups based on the obturating technique used, i.e., cold lateral condensation, warm ve