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Challenges of ADHD in Women and Girls Untreated ADHD symptoms can cause many issues for girls and women. They may feel inadequate at work, struggle with peer relationships or suffer from anxiety and depression. They are also more adept in establishing coping mechanisms that cover their ADHD symptoms, which makes it difficult for them to get diagnosed and treated. Signs and symptoms Although research has proven that ADHD affects men and boys at a higher rate than girls and women, the gender gap narr