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Pseudoprogression and hyperprogression are new radiologic response patterns with immunotherapy agents. It is critical to be aware of these two phenomena in order to make the right decisions for patients.Previous research into predictive inferences making showed that textual constraint influenced hemispheric processing of the inferences. However, the relationship between metacomprehension monitoring competence (MMC) and hemispheric processing of predictive inferences has rarely been investigated. The present study employed a divided visual