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form sinus fistula. These diagnoses are critical for pediatric surgeons or otolaryngologists in surgical planning.Correction of disease-causing mutations in human embryos holds the potential to reduce the burden of inherited genetic disorders and improve fertility treatments for couples with disease-causing mutations in lieu of embryo selection. Here, we evaluate repair outcomes of a Cas9-induced double-strand break (DS introduced on the paternal chromosome at the EYS locus, which carries a frameshift mutation causing blindness. We sh