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uDCD control pigs (n = 8), receiving no ex vivo perfusion, served as controls. Vascular resistance decreased to 200 mmHg/mL/min ( P 0.0023) and arterial flow increased to 100 mL/100 g/min ( P 0.00019) compared to controls. In total 13/21 study pigs survived for 10 days, while all uDCD control pigs died. Histology was preserved after reconditioning, and the creatinine level after 10 days was next to normal. Kidneys from extended uDCD, not receiving aCPR/EC, can be salvaged using thrombolytic treatment to remove fibrin