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001). In terms of mortality, high-dose ICS use was associated with increased mortality in multivariable Cox regression adjusted for age, sex, FEV and concomitant asthma/COPD (HR 4.93 [95% CI 1.73-14.0], p 0.003). In this cohort, close to one out of five patients with BE were prescribed ICS despite having no concomitant diagnosis of asthma or COPD. Overall, ICS treatment was associated with higher morbidity and mortality, though causation is difficult to establish. In this cohort, close to one out of five patients with BE were prescribed