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97 (95% CI0.94-1.0. The predictive value of G248T/S83I detection (the most common SNP, prevalence of 13% in the study population) was analysed with respect to treatment failure (patients received sequential doxycycline-moxifloxacin). The positive-predictive-value for moxifloxacin failure after detection of S83I was only 44% (95% CI24.4-65.1), while negative-predictive-value was high at 96.9% (95% CI92.7-99., suggesting that other SNPs are contributing to resistance.Conclusion. MG+parC(beta2) performed with high concordance compared