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Development in biotechnology is heralding an era of xenotransplantation. We highlight the physiologic considerations for xenogeneic grafts to achieve success.Progress in biotechnology is heralding a time of xenotransplantation. We highlight the physiologic considerations for xenogeneic grafts to achieve success. To know the indications and results of renal autotransplantation, and when to consider this original means of patients. Renal autotransplantation confers acceptably low rates of graft failure a