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The results suggest that the number of accounts tweeting suicidal-related themes decreased after the homicides, while the number of accounts posting offensive opinions and non-preventive advertisements increased. This implies that the efficacy of social media-based prevention measures may be undermined by this content.The small GTPase Ras homolog enriched in brain (Rheb) plays a critical role in activating the mechanistic target of rapamycin complex 1 (mTORC1), a signaling hub that regulates various cellular functions. We recently obse