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How Does ADHD Medication Work? Many people discover that ADHD medication helps them focus, concentrate and control their impulse-driven behavior. It can be a long process to find the right medication and dosage for every person. Certain medications can affect children's sleeping patterns. If they are sleeping better, it is a good sign that the medication is working. 1. Stimulants The most common prescription medication used by healthcare professionals to treat ADHD is stimulants. They work by increasing levels of certain chemicals (neurotra