https://tcs359inhibitor.com/pu....lse-rate-variation-i
In medical diagnostic scientific studies, the Youden index is a summary measure widely used into the evaluation of this diagnostic reliability of a medical test. Whenever covariates aren't considered, the diagnostic accuracy of this test is biased or misleading. By including information from covariates making use of linear regression designs, we propose general confidence intervals for the covariate-adjusted Youden index and its own optimal cut-off point. Furthermore, under heteroscedastic reg
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