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ise. It also demonstrates the study of the degradation pattern. Moreover, the above developed related substance analytical method was applied to the bulk analysis and pharmaceutical dosage form for routine analysis and stability study. The present study investigated the influence of simulated intraoral conditions (increased temperature and humidity) on two different surface pretreatment methods to repair a lithium-disilicate glass-ceramic (LDS). A total of 540 rectangular lithium-disilicate glass-ceramic bar