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Pathway evaluation identified multiple gene-sets (proliferation, migration, and irritation) that have been somewhat down-regulated in ER-positive tumors of females with high 25(OH)D (≥30ng/ml), compared to people that have low levels. 25(OH)D score derived ended up being marginally associated with just minimal risk of recurrence in ER-positive conditions in NHS, however, no organization had been noted when you look at the replication dataset. CONCLUSIONS Our findings support