https://www.selleckchem.com/pr....oducts/pf-05221304.h
The value of the offset is predominantly determined by the substrate material, with the thermocouple tip temperature being lower than the average skin surface temperature by 1-5 °C and 3-10 °C for steel and aluminum substrate cases, respectively. This temperature difference results in a moderate to an extreme thermocouple underprediction of the time necessary for the skin surface to reach the experimental safety threshold of 1 °C. Consequently, from the perspective of the safety related applications the thermocouple measurement prov