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On the other hand, the water environment of sequencing batc reactor has turned into a pitch dark state at 500 mg/L paracetamol feeding. As a result, aerobic bacteria preferred paracetamol rather than oxytetracycline. In other words, aerobic bacteria preferred paracetamol/oxytetracycline as the second electron acceptor after O2.Bioconversion of glycerol to 1,3-propanediol is a promising way to mitigate the shortage of energy. To maximize the production of 1,3-propanediol, it needs to control precisely microbial fermentation process. How