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ting the severity of intra-amniotic infection. •The closer the placental lesions are to the fetus, the higher the content of serum sialic acid is. • The value of serum sialic acids of preterm infants within 1-hour afterbirth may be one of the rapid postnatal biomarkers for evaluating the severity of intra-amniotic infection. • The closer the placental lesions are to the fetus, the higher the content of serum sialic acid is.To explore the current state of research on off-label drug use in children and identify the ex