https://www.selleckchem.com/pr....oducts/pf-07220060.h
This study intended to investigate whether exposure to the combination of noise and Ag-NPs in rats induces cochlear damage and hearing dysfunction. A total of 24Wistar rats were divided into four treatment groups and received/exposed to saline (IP), Ag-NPs (100mg/kg, 5d/w for 4weeks), 8kHz narrowband noise (104dB SPL, 6h/day, 5d/w for 4weeks) and Ag-NPs plus noise. The DPOAE, serum levels of MDA and SOD and changes in body weight were assessed. The rat cochlea was further stained for investigating the mRNA expression (TL-6, NOX3, an
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