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eement for the self-assessment with the MSF was fair ( = 0.386; 0.001). The Portuguese variant of the MCTQ revealed to be a reliable questionnaire to assess the chronotype for the Portuguese adult population, as previously reported for other countries. The Portuguese variant of the MCTQ revealed to be a reliable questionnaire to assess the chronotype for the Portuguese adult population, as previously reported for other countries.The developmental role of Lef-1 in ectodermal organs has been characterized using Lef-1 murine knockout