https://www.selleckchem.com/pr....oducts/incb084550.ht
ι-Carrageenan performs diversified biological activities but has low bioavailability. ι-Carrageenan tetrasaccharide (ιCTs), a novel marine oligosaccharide prepared by the marine enzyme Cgi82A, was investigated for its effects on insulin resistance in high-fat and high-sucrose diet mice. Oral administration of ιCTs (ιCTs-L 30.0 mg/kg·bw, ιCTs-H 90.0 mg/kg·bw) decreased fasting blood glucose by 35.1% ± 1.41 (P less then 0.01) and 27.4% ± 0.420 (P less then 0.05), and enhanced glucose tolerance. Besides, ιCTs-L ameliorated islet vacuoli