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ave a significant effect on the ANS in patients with LC, causing the predominance of the sympathetic branch activity over the parasympathetic one. Oxidative stress, triggering the relevant pathogenetic mechanisms has an effect on the autonomic nervous system in patients with liver cirrhosis. However, the realization of the dominant influence of the sympathetic branch of the autonomic nervous system is minimized due to the decrease in the sensitivity of receptors to vasoconstrictors, including to neurotransmitters.The article is devote