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h an idea of the goodness of the fit. When assessing simplifications of methods for calculation of the absorbed dose to the kidneys, it was of the uttermost importance to incorporate the fractional contribution for the extrapolations included in the reference method. Measurements at an early and a late time point were found most important. An intermediate measurement contributes with an idea of the goodness of the fit. The human mandible is variable in shape, size and position and any deviation from normal can affect the facial appeara