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Male BMVECs secreted more ET-1. Hypoxia increased ET-1 in both cell types. There are sex differences in the stroke and diabetes-mediated changes in the brain ET system at endothelial and tissue levels.Although ibrutinib-associated atrial and ventricular arrhythmias have been well described, there is little information about ibrutinib's effects on other electrocardiographic parameters, particularly the QT interval. Using our database of 137 patients treated with ibrutinib, we retrospectively identified 21 patients in whom an electrocardi
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