https://pdgfrsignals.com/index.....php/striking-the-go
Results Our results suggested that germacrone treatment dramatically inhibited cell proliferation by inducing apoptosis in a dose-dependent manner, with IC50 values of 259 μM for PC-3 cells and 396.9 μM for 22RV1 cells. Germacrone-treated cells additionally exhibited induction of autophagy, as evidenced by elevated LC3B-II necessary protein phrase levels and punctuate patterns. Also, an autophagy inhibitor enhanced the growth inhibitory aftereffect of germacrone. Additionally, the phosphorylation
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