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ADHD Treatment Medication Adults who suffer from ADHD are usually treated with medication and psychosocial therapy. Medications used to treat ADHD include stimulants as well as non-stimulant medication. Stimulants such as methylphenidate or Lisdexamfetamine work on chemical messengers in the brain to improve concentration, mood, and impulse control. Atomoxetine and Guanfacine are both non-stimulant ADHD medicines that may be given to teenagers, adults or children if they do not respond to stimulant