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It was also observed that in 41% of the cases a successful outcome was contingent upon willingness of the applicant to restrict the indication. A majority of oncology procedures that had an OE resulted in a positive outcome suggesting that such agency interaction is an important opportunity for the applicant to have a last chance to resolve any outstanding issues at the final stage of the procedure. A majority of oncology procedures that had an OE resulted in a positive outcome suggesting that such agency interaction is an important o