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Rationale Obesity is associated with an increased risk of pulmonary hypertension (PH), however regional adipose tissue deposition is heterogeneous with distinct cardiovascular phenotypes. Objective To determine the association of body mass index (BMI), thoracic visceral and subcutaneous adipose tissue areas (VAT and SAT, respectively) with PH in patients with advanced lung disease referred for lung transplantation. Methods We studied patients undergoing evaluation for lung transplantation at 3 centers from the Lung Transplant Body Com