https://www.selleckchem.com/pr....oducts/chaetocin.htm
The occurrence and development of an endemic osteoarthritis Kashin-Beck Disease (KBD) is closely related to oxidative stress induced by free radicals. The aim of the study was to find the key signalling molecules or pathogenic factors as a potential treatment strategy for KBD. Real-time PCR and western blotting were performed to detect the mRNA and protein expression levels in cells and tissues. Immunohistochemical staining was assayed in rat models and human samples obtained from children. The type of cell death was identified by Ann