https://www.selleckchem.com/pr....oducts/resiquimod.ht
To evaluate the safety and feasibility of a newly designed I brachytherapy ureteral stent (BUS) in normal dogs. A BUS loaded with 10 I seeds (Group A 0.8mCi, Group B 0.4mCi, Group C 0mCi) was designed and tested in 27 normal beagle dogs. Routine blood tests, gross observations, cumulative radiation doses, tissue reaction assessed by hematoxylin-eosin/Masson staining, mRNA analysis by RT-qPCR and protein expression of Caspase-3, Collagen I, PCNA, and α-SMA were performed at 2, 4 and 8weeks. The BUS was implanted successfully in all do
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