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ADHD Medication Medication is often a part of an ADHD treatment strategy. The two most popular stimulant drugs are dextroamphetamine as well as methylphenidate. Each of these has many brand names and each has a different chemical makeup. Stimulants increase brain chemicals that aid in transmitting messages between neurons. These are the first medication that healthcare providers usually try for adults with ADHD. Stimulants Most doctors prescribe stimu