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The PNPLA3 (adiponutrin) p.I148M polymorphism improves the threat of liver injury. The purpose of our study would be to research the relationship involving the procholestatic ABCB4 polymorphism c.711AT and LSM ≥ 9.1 kPa in people along with the connection between ABCB4 and PNPLA3 in a mouse type of chronic cholestasis. Prospectively, we recruited 712 patients with CLD (278 females, age 50 ± 13 years) with available TE results; liver biopsy results were for