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The RSV-loaded INU-F68-SA nanomicelles (RSNM) had about 172 nm size, spherical form, 0.237 polydispersity index, and -18 mV zeta potential. Moreover, the RSNM showed large medication entrapment efficiency, controlled medicine release and protection of medication during storage space. The RSNM somewhat enhanced the cytotoxicity of RSV against colorectal disease cells by inducing apoptosis and switching mitochondrial membrane potential. More, in-vivo pharmacokinetic experiment