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The latter behaviour can be modelled as a novel assisted diffusion system, that might allow virus particles to explore the cytoplasm better. Cytoplasmic dynein and Kif5B have both been found to bind AdV through direct communications with all the capsid proteins Hexon, and Penton Base, respectively. We review here the roles of this microtubule motor proteins in AdV illness, the relationship between motor protein recruitment to pathogenic vs. physiological cargoes, the evolutionary beginnings o
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