https://www.selleckchem.com/pr....oducts/ici-118551-ic
Finally, animal experiments were performed to demonstrate the effect of MIR22HG on the radiosensitivity of hepatoma. Irradiation can up-regulate MIR22HG expression and down-regulate HDAC2 expression. Inhibition of HDAC2 expression promotes histone acetylation in the MIR22HG promoter region and up-regulates MIR22HG expression. MIR22HG can increase radiosensitivity miR-22-5p in HCC. Inhibition of HDAC2 expression promotes histone acetylation in the MIR22HG promoter region, thereby up-regulating the expression of MIR22HG and
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