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Hypothyroidism (HT) is a well-known complication of radiation (RT) that includes supraclavicular (SCV) fields. We analyzed breast cancer patients who received SCV-directed RT to evaluate predictors of HT and developed the first normal tissue complication probability (NTCP) model for HT specific to breast cancer patients. 192 breast cancer patients received SCV-directed RT between 2007 and 2019 and met inclusion criteria. #link# Individual dose-volume histograms were analyzed to determine thyroid volume within and outside specific isodos