https://histaminereceptor.com/....index.php/health-sys
SERCA2a is acetylated, and therefore acetylation is more prominent in failing personal hearts. In this research, we verified that p300 interacts with and acetylates SERCA2a in cardiac areas. Several lysine residues in SERCA2a modulated by p300 had been identified making use of in vitro acetylation assay. Evaluation of in vitro acetylated SERCA2a disclosed several lysine deposits in SERCA2a vunerable to acetylation by p300. Included in this, SERCA2a Lys514