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To assess time-trends and outcomes of hallucinogen use disorder hospitalizations. The U.S. National Inpatient Sample (NIS) data from 1998 to 2014 were used. People hospitalized with hallucinogen use disorder as primary or secondary diagnosis were assessed. Rates were calculated per 100,000 NIS claims. Multivariable-adjusted logistic regression analyses assessed the association of patient and hospital characteristics with outcomes. The national U.S. rates per 100,000 total NIS claims for hallucinogen use disorder hospitalizations increas