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Non Stimulant and Stimulant ADHD Medications The medications are an important element of the ADHD treatment strategy. However, choosing the right one can be a long process that depends on medical history as well as genetics and side effects. Stimulant medications like methylphenidate or amphetamine increase certain chemicals in the mind that aid in focusing and manage their impulses. They also reduce hyperactivity. They're the first choice for many people with ADHD. Strattera Strattera is a prescription drug that has been approved by the FDA