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Background The aim of this study was to evaluate the effectiveness of a tailored treatment dental program in adolescents in combination with a professional oral hygiene. Methods Ninety-three adolescents (43 males and 50 females; mean age 14±1.1 years) were included in this study and Plaque Index (PI) and simplified basic periodontal examination (BPE) were measured for each patient at T0 (screening) and at T1 (after 30 days). At T0 a professional dental hygiene treatment was performed and a tailored oral hygiene instruction protocol was a