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Within silicotic granulomas, collagen V and FIZZ1 enhanced, while peroxisome proliferator-activated receptor gamma (PPARγ) good cells decreased. In inclusion, the phrase of proteins Notch-1, alpha smooth muscle tissue actin (α-SMA) and macrophages163 (CD163) were higher in silicotic granulomas than control lungs. A substantial good correlation ended up being found between collagen V and FIZZ1 (r = 0.70; p less then 0.05), collagen V and Notch-1 (roentgen = 0.72; p less