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The causal commitment between obesity and high blood pressure is set up; however, the step-by-step paths for such organization are nevertheless under analysis. This work aims to gauge the changes in neprilysin, vasoconstrictor and vasodilatory particles in obese hypertensive patients undergoing laparoscopic sleeve gastrectomy (LSG). The present potential research was done on 59 hypertensive overweight patients in who LGS had been performed. Blood pressure, as well as blood samples for neprilysin, an