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This research aimed to study the results of long-term management of AHs on intellectual (memory, state of mind, interest, rest and executive function) and psychomotor performance. This potential, observational research for a complete duration of 30 months was carried out in the Dermatology OPD in person patients with dermatological problem have been newly recommended either chlorpheniramine (4 mg, BD), levocetirizine (10 mg, OD), fexofenadine (180 mg, OD) or bepotastine (1