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ADHD Medications - Stimulant Or Non Stimulant? For many people stimulant medication is the first choice for treating ADHD. Some suffer from adverse reactions or they don't perform as well. Some doctors prescribe stimulants in addition to non-stimulant ADHD medications. These include medicines that treat high blood-pressure like clonidine or guanfacine (Tenex). They also include other medications that help to increase wakefulness. Benefits The first drug