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Purpose To compare a novel Thulium laser device with the commonly used HolmiumYttrium-Aluminum-Garnet (HoYAG) laser in terms of the in vitro temperatures generated. Methods Our study investigated and compared an evaluation model of a solid-state Thulium laser with a Medilas H Solvo 35 Holmium laser device, both by Dornier (Dornier MedTech Laser GmbH, Wessling, Germany). Our in vitro model consisted of a 20 mL test tube placed in a 37°C water bath. Constant irrigation was set at 50 mL/minute with a Reglo Z Digital pump (Cole Parmer, Chicago, IL). Four hundre