https://www.selleckchem.com/pr....oducts/VX-680(MK-045
Ischemic placental disease (IPD), including preeclampsia, abruption, and fetal growth restriction, often recurs in subsequent pregnancies. Angiogenic factors of placental origin have been implicated in the pathogenesis of preeclampsia, but have not been studied as predictors of IPD in subsequent pregnancies. We hypothesized that elevated angiogenic factors in an index pregnancy would be associated with recurrence of IPD. We conducted a retrospective cohort study of patients undergoing evaluation for preeclampsia who had angiogen