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IFNα has been confirmed to cause medical, hematological, molecular, and histopathological remission, but its toxicity has actually remained a limitation of the much more extensive use. The development of pegylated kinds with a far better threshold has brought brand-new alternatives for customers. State III clinical trials, ropeginterferonα versus hydroxyurea PROUD-PV and CONTINUATION-PV, demonstrate lasting superiority in the efficacy and protection when comparing ropeginte
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