https://www.selleckchem.com/pr....oducts/pimicotinib.h
The significance level was 5%. There was no statistically significant difference between the groups for the absolute risk of TS (p = 1.0 or for the intensity of TS (p 0.05). A bleaching of approximately 7 shade guide units was observed on the Vita Classical and Vita Bleachedguide scales, with no statistical difference between the groups. It was concluded that coadministration of ibuprofen and caffeine did not reduce the absolute risk or intensity of TS and did not interfere with the efficacy of dental bleaching.The host defen